Pleiotropic effects of type 2 diabetes management strategies on renal risk factors.

Pleiotropic effects of type 2 diabetes management strategies on renal risk factors.

In parallel with the type 2 diabetes pandemic, diabetic kidney disease has become the leading cause of end-stage renal disease worldwide, and is associated with high cardiovascular morbidity and mortality. As established in landmark randomised trials and recommended in clinical guidelines, prevention and treatment of diabetic kidney disease focuses on control of the two main renal risk factors, hyperglycaemia and systemic hypertension.

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