Metformin–mode of action and clinical implications for diabetes and cancer.

Metformin–mode of action and clinical implications for diabetes and cancer.

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Metformin has been the mainstay of therapy for diabetes mellitus for many years; however, the mechanistic aspects of metformin action remained ill-defined. Recent advances revealed that this drug, in addition to its glucose-lowering action, might be promising for specifically targeting metabolic differences between normal and abnormal metabolic signalling.

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