Hormone May Explain Origin Of Type 2 Diabetes In Children

Hormone May Explain Origin Of Type 2 Diabetes In Children

This post was originally published on this site

Because leptin helps regulate insulin secretion and blood glucose levels, researchers believe that dysregulation of the hormone during prenatal development could explain the connection to type 2 diabetes. “We showed that exposure of the embryonic mouse brain to leptin during a key developmental period resulted in permanent alterations in the growth of neurons from the brainstem to the pancreas, resulting in long-term disturbances to the balance of insulin levels in the adult mouse,” said Sebastien G. Bouret, PhD, researcher in the developmental neuroscience program at CHLA.

Start the conversation, or Read more at Battle Diabetes.